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Nutritional Supplement Store SAME Offering is as of March 2004. Click through for current info, pricing, and availability. Nutritional Supplements > Life Extension Nutritional Supplements > Item 3      SAME energy stress stamina Safety Information Keep lid tightly closed. Keep out of reach of children. Product Description SAMe (S-adenosyl-methionine) is an amino acid derivative normally synthesized in the body. SAMe is used by the body in three important pathways: 1) Methylation (contributing methyl groups to activate certain molecules). 2) The synthesis of polyamines (for cell growth, gene expression, neuronal regeneration, etc.) 3) Trans-sulfuration (synthesis of cysteine, glutathione, and other sulfate chemicals). In young, healthy people SAMe is well distributed throughout the body as a result of its synthesis from methionine by enzymes using ATP. Directions One tablet before meals in the morning and one in the afternoon.May be increased by taking one tablet in the morning and two tablets in the afternoon and for some people an additional tablet in the evening.After two weeks a maximum dose of two tablets in the morning,two in the afternoon, and two in the evening can be taken. Legal Disclaimer *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.