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Nutritional Supplement Store Same 2x :: 30 ct Offering is as of March 2004. Click through for current info, pricing, and availability. Nutritional Supplements > S-Adenosyl-L-Methionine > Item 14      Same 2x :: 30 ct Product Description SAMe is a supplement formed in the body by an enzymatic reaction between adenosine-triphosphate (ATP) and methionine. It was discovered in 1952 in Italy and has been researched and manufactured there. SAMe works closely with folic acid and vitamin B-12, and functions as a methyl donor. This nutrient carries and donates methyl molecules necessary to facilitate the manufacture of DNA and brain neurotransmitters. Tissue levels of SAMe are typically low in the elderly. Warnings: Individuals with bipolar (manic) depression should not take SAMe unless under professional medical supervision. Per 1 Enteric Coated Tablet: Vitamin B-6 (as Pyridoxine HCl) 2mg 100%, Folic Acid 200mcg 50%, Vitamin B-12 (as Cyanocobalamin) 50mcg 833%, S-Adenosyl L-Methionine Disulphate Tosylate (providing 200mg, S-Adenosyl L-Methionine "SAMe") 400mg ( % Daily Values). Other Ingredients: Cellulose, Mannitol, Hydroxypropyl Methylcellulose Phthalate, Citric Acid, Sodium Starch Glycolate, Glyceryl Triacetate, Croscarmellose Sodium, Stearic Acid, Silica and Titanium Dioxide. Legal Disclaimer These products and these statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Consult a health care professional before using these or any product during pregnancy or if you have a serious medical condition.